RecruitingNCT07329712

Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy


Sponsor

Singapore National Eye Centre

Enrollment

30 participants

Start Date

Nov 5, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response. Low-level light therapy is light-based treatment delivered through advance eye-light device. This therapy uses light energy to provide energy to the meibomian gland cells to slow down age-ing, improve tear stability and reduce inflammation.


Eligibility

Min Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how low-level light therapy (a gentle, non-invasive light treatment applied near the eyes) affects proteins found in tears in patients with dry eye disease. By analyzing tear proteins before and after treatment, researchers hope to better understand how the therapy works and identify markers of response. **You may be eligible if...** - You are 21 years or older - You have been assessed as eligible for low-level light therapy for dry eye disease - You have not come to the clinic for an acute eye emergency (like sudden vision loss or severe eye pain) - You are able to give informed consent **You may NOT be eligible if...** - You are pregnant - You have a pacemaker, metal implants, or acoustic prosthetics - You have epilepsy, heart rhythm problems, uncontrolled high blood pressure, or severe diabetes - You have open wounds on your eyelids or nearby skin - You have active cancer or hepatitis - You are on blood thinners or have a clotting disorder - You have had venous surgery or have large varicose veins in the past 2 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Singapore Eye Research Insititute

Singapore, Singapore

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NCT07329712


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