RecruitingNCT07329712
Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy
Sponsor
Singapore National Eye Centre
Enrollment
30 participants
Start Date
Nov 5, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response. Low-level light therapy is light-based treatment delivered through advance eye-light device. This therapy uses light energy to provide energy to the meibomian gland cells to slow down age-ing, improve tear stability and reduce inflammation.
Eligibility
Min Age: 21 Years
Inclusion Criteria4
- Must be eligible for, and have consented for low level light therapy
- Must not have presented to the clinic for an acute eye problem such as visual loss or painful eye
- Ability to give informed consent.
- Age more or equals to 21 years old.
Exclusion Criteria12
- Patients who are unable to or decline to give consent.
- Age less than 21 years old.
- Patients who presented to the clinic for an acute eye problem such as visual loss or painful eye.
- Patients not suitable for low level lighttherapy:
- Pregnant
- Fitted with pacemakers, metal, electrical, acoustic prosthetics
- Epilepsy, cardiac rhythm or frequency disorders
- Fever, thrombophlebitis or acute phlebitis of the legs, large-sized varicose veins, or venous surgery within 2 months
- Uncontrolled hypertension or severe diabetes
- Open wounds on eyelid or skin
- Evolving cancer or hepatitis
- Blood anticoagulant or coagulation defect
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07329712
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