RecruitingNCT07336173

Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm Labor

Role of Uterine Artery Doppler Indices and Sonographic Measurement of Uterocervical Angle in Predicting Preterm Labor


Sponsor

Kafrelsheikh University

Enrollment

47 participants

Start Date

Jan 15, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to evaluate the role of uterine artery doppler indices and uterocervical angle measurement in prediction of preterm labor .The main question it aims to answer is: Does combination of both uterine artery doppler indices and uterocervical angle measurement increase sensitivity and specificity for prediction of established preterm labor ? Participants already performing uterine artery doppler as part of their regular antenatal care .measurement of anterior uterocervical angle will be added between 24 to 34 weeks gestation to predict preterm labor in candidates .


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Inclusion Criteria7

  • Patient who will give verbal \& written will informed consent.
  • Pregnant women between 18 and 40 years old of age
  • Singleton pregnancy
  • Gestational age will be confirmed by first trimester ultrasound scan (\<14 weeks).
  • Gestational age between 24 and 34 weeks .
  • Threatened preterm labor which is defined as:
  • Presence of at least one uterine contraction every 10 minutes lasting ≥30 seconds . Cervical dilatation ≤3 cm . Cervical effacement \<80%.

Exclusion Criteria12

  • Obstetric:
  • Ruptured membranes
  • Clinical evidence of Chorioamnionitis.
  • Fetal compromise on evaluation.
  • Severe obstetric complications (e.g., severe Preeclampsia, Eclampsia).
  • Diagnosed intrauterine growth restriction (IUGR).
  • Congenital fetal anomalies.
  • Multiple pregnancies.
  • Prior cervical surgery (e.g., cone biopsy, cerclage).
  • Non-Obstetric:
  • Significant maternal medical disorders (e.g., chronic hypertension, diabetes mellitus, liver dysfunction).
  • Severe non-obstetric complications (e.g., acute abdomen).

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Interventions

DEVICEUltrasound

Trans abdominal ultrasound will be used to measure uterine artery doppler indices Trans vaginal ultrasound will be used to measure anterior uterocervical angle


Locations(1)

Kafr elsheikh university hospital

Kafr ash Shaykh, Egypt

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NCT07336173


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