RecruitingPhase 3NCT07336368

Topical Cryotherapy and Keloid/Hypertrophic Scars

Topical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot Study


Sponsor

Sonal Choudhary

Enrollment

30 participants

Start Date

Jun 10, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it aims to answer are: Does topical cryotherapy applied before intralesional triamcinolone injection impact pain perceptions for participants with keloids or hypertrophic scars? Does topical cryotherapy affect provider-assessed injection resistance compared with standard injection alone? Researchers will split the keloid/hypertrophic scar into two halves. One half will be treated with cryotherapy followed by steroid injection, while the other half will be treated with steroid injection alone to evaluate differences in pain perception and injection resistance. Participants will rate pain after each injection using a 10-point numeric pain scale. Clinicians will rate the resistance after each injection using a 10-point numeric scale.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Cryotherapy with liquid nitrogen and a drug called Intralesional Triamcinolone 10 mg/ml for people with keloid scars and hypertrophic scars. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICECryotherapy with liquid nitrogen

liquid nitrogen spray (\~10 seconds)

DRUGIntralesional Triamcinolone 10 mg/ml

Intralesional triamcinolone


Locations(1)

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

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NCT07336368


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