Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx
University Hospital, Strasbourg, France
30 participants
Jul 11, 2025
OBSERVATIONAL
Conditions
Summary
The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor. However, obtaining this complete assessment can delay treatment. Confirmation of the non-inferiority of 40keV dual-energy CT in BOLT compared to MRI would spare the patient an additional MRI examination, speed up the pre-treatment assessment, reduce the loss of opportunity due to delayed treatment, and free up MRI imaging slots, which are still insufficient in the region.
Eligibility
Inclusion Criteria5
- Adult patient (≥18 years)
- presenting with oral or oropharyngeal squamous cell carcinoma proven by histopathological analysis of a biopsy
- having undergone a clinical examination with nasofibroscopy by an ENT surgeon specializing in cancer surgery
- a contrast-enhanced cervicofacial MRI
- and a contrast-enhanced cervicofacial DECT with BOLT maneuver.
Exclusion Criteria3
- A lesion other than oral or oropharyngeal squamous cell carcinoma
- A labial location
- A contraindication to performing one or both of the imaging examinations.
Locations(1)
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NCT07343271