RecruitingNCT07343271

Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx


Sponsor

University Hospital, Strasbourg, France

Enrollment

30 participants

Start Date

Jul 11, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor. However, obtaining this complete assessment can delay treatment. Confirmation of the non-inferiority of 40keV dual-energy CT in BOLT compared to MRI would spare the patient an additional MRI examination, speed up the pre-treatment assessment, reduce the loss of opportunity due to delayed treatment, and free up MRI imaging slots, which are still insufficient in the region.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two types of detailed imaging — dual-energy CT (DECT) and MRI — to see which is better at assessing the extent of squamous cell cancers of the mouth and throat (oral cavity and oropharynx) before surgery. Better imaging could help surgeons plan more precise operations. **You may be eligible if...** - You are 18 or older - You have a confirmed squamous cell carcinoma of the mouth or throat (oral cavity or oropharynx) - You have already had an ENT specialist examination and received both a contrast-enhanced MRI and a dual-energy CT scan as part of your staging workup **You may NOT be eligible if...** - Your cancer is a different type (not squamous cell) - Your tumour is on the lips - You cannot have one or both of the imaging scans (e.g., MRI contraindication) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Service d'ORL et de Chirurgie Cervico-faciale - CHU de Strasbourg - France

Strasbourg, France

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NCT07343271


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