RecruitingNot ApplicableNCT07345715

Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy

Comparison Between Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy: A Prospective, Randomized Controlled Trial


Sponsor

Tanta University

Enrollment

96 participants

Start Date

Jul 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare the efficacy of using oral Melatonin versus nebulized Dexmedetomidine in limitation of emergence agitation in children undergoing adenotonsillectomy.


Eligibility

Min Age: 3 YearsMax Age: 7 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nebulized dexmedetomidine, a drug called Normal saline, and others for people with children, nebulized dexmedetomidine, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 3 Years to 7 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNormal saline

Participants will receive placebo nebulizer (3 ml of normal saline) without drug and 0.5 mg/kg of midazolam dissolved in Apple Juice.

DRUGOral melatonin syrup

Participants will receive placebo nebulizer (3 ml of normal saline) without drug and 0.2 mg/kg of oral melatonin syrup.

DRUGNebulized dexmedetomidine

Participants will receive placebo syrup (Apple Juice) and 2 µ/kg nebulized dexmedetomidine prepared in 0.9% normal saline to a final volume of 3ml.


Locations(1)

Tanta University

Tanta, El-Gharbia, Egypt

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NCT07345715


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