RecruitingNCT07348757

rFSH vs rFSH+rLH in Dydrogesterone-Based Progestin Protocol: A Prospective Study

Comparison of rFSH Alone Versus rFSH+rLH in Dydrogesterone-Based Progestin Protocol Cycles


Sponsor

Centrum Clinic IVF Center

Enrollment

300 participants

Start Date

Jan 5, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to compare two commonly used hormone treatments for women undergoing IVF. All participants will receive a stimulation protocol that includes dydrogesterone, a medication used to safely control natural hormone surges during treatment. The study will observe women who are treated either with recombinant FSH alone or with a combination of recombinant FSH and recombinant LH-both routinely used options in our clinic. Investigators will prospectively monitor how these treatments affect the growth of ovarian follicles, the number of mature eggs collected, the quality of developing embryos, and early pregnancy outcomes. No additional procedures or medications will be required beyond standard IVF care. The goal is to better understand whether adding recombinant LH provides any measurable benefit in dydrogesterone-based PPOS cycles.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 43 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with gonadotropins and invitro fertilization. The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

Centrum Clinic IVF Center

Ankara, Ankara, Turkey (Türkiye)

Bahçeci IVF Center

Ankara, Turkey (Türkiye)

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NCT07348757


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