RecruitingNCT07356570

Second Prospective Cohort of Patients Entering the Multidisciplinary Care Pathway for Post-Covid Syndromes - SyPoCo2 Cohort

Sponsor

Hospices Civils de Lyon

Enrollment

150 participants

Start Date

Jun 13, 2025

Study Type

OBSERVATIONAL

Conditions

Post-Acute COVID-19 Syndrome

Summary

The study aims to identify clinical profiles of long-COVID patients and correlate them with immunological and molecular data in order to identify prognostic biomarkers and potential therapeutic targets.

Eligibility

Min Age: 18 Years

Inclusion Criteria6

Documented SARS-CoV-2 infection
Persistent or complex post-COVID symptoms lasting more than 4 weeks or more than 3 months
Patient referred to the EPSILON pathway or to the post-COVID rehabilitation unit
Age ≥ 18 years
Non-institutionalized
Expected survival greater than 6 months

Exclusion Criteria5

Refusal to participate or to share data
Uncontrolled comorbidities
Pregnant or breastfeeding women
Persons under legal protection or deprived of liberty
Not affiliated with the French national health insurance system

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Interventions

OTHERBlood sample collection

A one-time 30 mL blood draw is performed during the inclusion visit for immunological and molecular analysis as part of the HERVCOV research program. No therapeutic intervention is administered, and no samples are stored after analysis.