Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children
Comparative Evaluation of Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children: A Randomized Controlled Clinical Trial
Al-Azhar University
66 participants
Aug 15, 2025
INTERVENTIONAL
Conditions
Summary
This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of Egyptian schoolchildren.
Eligibility
Inclusion Criteria4
- Healthy Egyptian schoolchildren aged 6-12 years.
- Good general health.
- Mild to moderate dental plaque accumulation.
- Parental/caregiver willingness to provide consent
Exclusion Criteria4
- Antibiotic or antimicrobial use within the last month.
- Allergies to the mouthwash components.
- Systemic diseases affecting oral health.
- Orthodontic appliances or extensive dental restorations.
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Interventions
Patients will be receive probiotic mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.
Patients will be treated with ethyl lauroyl arginate mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.
Patients will receive professional prophylaxis (scaling + polishing) at baseline and will use only regular toothpaste twice daily, with no adjunctive mouthwashes over 28 days.
Locations(1)
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NCT07356869