Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With Depression

This study is investigating whether omega-3 fatty acid supplements (like fish oil) can reduce inflammation, improve mood, and support healthy gut bacteria in young people diagnosed with a major depressive episode (MDE). **You may be eligible if...** - You are a young person with a diagnosed major depressive episode (MDE) according to standard psychiatric criteria **You may NOT be eligible if...** - You have changed your antidepressant medication or started/stopped therapy within the past 4 weeks - You are allergic to omega-3 fatty acids (found in fish oil) Talk to your doctor to see if this trial is right for you.