RecruitingNCT07370948

Study of the Antibiotic-resistance Profile of Enterobacterales Isolated From Rectal Mucosal Buffer of PrEP Subjects


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

200 participants

Start Date

May 30, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The importance of the study lies mainly in expanding knowledge of the phenomenon of antibiotic resistance in subjects using PrEP, studying for the first time in this population the resistance phenotype in commensal Enterobacterales of the gastrointestinal tract. The data obtained from this study could pave the way for potential surveillance and awareness programs for the critical and conscious use of antimicrobials in PrEP subjects in order to mitigate the problem of antibiotic resistance, which currently represents a real global challenge.


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Inclusion Criteria2

  • age between 18 and 45 years
  • HIV-negative subjects undergoing an anorectal swab for Chlamydia trachomatis and Neisseria gonorrhoeae using NAAT as a normal diagnostic-assistance procedure provided for subjects using PrEP

Exclusion Criteria1

  • none

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Locations(1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, Italy

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NCT07370948


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