Outcomes of Couples After Failed PGD Management: A Single-Center Study at the Paris PGD Center (Antoine Béclère - Necker)
Assistance Publique - Hôpitaux de Paris
900 participants
Mar 25, 2026
OBSERVATIONAL
Conditions
Summary
Preimplantation genetic testing (PGT) is a reproductive genetic technique aimed at preventing the transmission of severe genetic disorders. In France, its use is strictly regulated and reserved for complex medical situations, often associated with challenging reproductive histories and significant psychological burden. Despite scientific advances, success rates in preimplantation genetic testing remain limited, making the care pathway a significant source of uncertainty regarding the future of the parental project.
Eligibility
Inclusion Criteria4
- Woman belonging to a couple who initiated at least one ovarian stimulation cycle for IVF (± ICSI) with preimplantation genetic diagnosis (PGD).
- No further PGD-related procedures (oocyte retrieval or embryo transfer) performed in the center after December 31, 2022.
- No live-born child resulting from PGD care.
- Woman who expressed her free and informed non-opposition to participation.
Exclusion Criteria2
- One or more live-born children resulting from PGD care in the center.
- PGD involving gamete donation.
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Locations(1)
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NCT07371312