RecruitingNot ApplicableNCT07374289

On Scene ECPR in Ostrava

The Effectiveness of ECPR on the Scene and in Hospital for Out-of-hospital Cardi-ac Arrest (OHCA) in the Moravian-Silesian Region.


Sponsor

University Hospital Ostrava

Enrollment

90 participants

Start Date

Jan 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

On-scene extracorporeal pulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) seems to speed up the start of extracorporeal membrane oxygenation (ECMO) and shorten low flow during cardiopulmonary resuscitation (CPR) in case of refractory cardiac arrest. The primary goal is to verify the benefit of on-scene ECPR in terms of shortening the collapse-to-ECMO interval. The secondary goal is to compare outcomes in the on-scene ECPR group with hospital cannulation.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria5

  • Presumed cardiac aetiology of the cardiac arrest
  • Witnessed collapse
  • Bystander CPR
  • Estimated age ≤ 70 years
  • Body weight ≥15 Kg

Exclusion Criteria2

  • Known terminal malignant disease
  • Known terminal chronic disease

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Interventions

PROCEDUREPrehospital ECMO cannulation on scene of cardiac arrest

ECPR (Extracorporeal Cardiopulmonary Resuscitation) is a critical, advanced resuscitation technique using Veno-arterial Extracorporeal Membrane Oxygenation for patients in cardiac arrest where conventional CPR fails, functioning as a bridge to restore circulation and oxygenation by pumping and oxygenating blood outside the body before returning it.

PROCEDURETransfer with ongoing mechanical chest compression to hospital followed by hospital ECMO cannulation

ECPR (Extracorporeal Cardiopulmonary Resuscitation) is a critical, advanced resuscitation technique using Veno-arterial Extracorporeal Membrane Oxygenation for patients in cardiac arrest where conventional CPR fails, functioning as a bridge to restore circulation and oxygenation by pumping and oxygenating blood outside the body before returning it.


Locations(2)

Emergency Medical Services, Moravian-Silesian Region

Ostrava, Moravian-Silesian Region, Czechia

University Hospital Ostrava

Ostrava, Moravian-Silesian Region, Czechia

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NCT07374289


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