RecruitingNCT07375433

Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinical Course and Prognosis

Sponsor

National Medical Research Center for Therapy and Preventive Medicine

Enrollment

200 participants

Start Date

Jan 1, 2026

Study Type

OBSERVATIONAL

Conditions

COPD, Chronic Obstructive Pulmonary Disease Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)

Summary

Study aim is comparison of heart failire with preserved ejection fraction (HFpEF) detection rate in patients with Сhronic Obstructive Pulmonary Disease (COPD) and the clinical course and prognosis in patients with COPD depending on HFpEF presence.

Eligibility

Min Age: 50 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study looks at how heart failure with preserved pumping function develops and progresses in people who also have chronic obstructive pulmonary disease (COPD), a lung condition that makes it hard to breathe. **You may be eligible if...** - You have a confirmed COPD diagnosis - You are currently hospitalized for COPD - You are a citizen of the Russian Federation - You are between 50 and 70 years old - You are willing to give your consent to participate **You may NOT be eligible if...** - You are not a Russian citizen - You have other serious chronic illnesses (besides COPD) that are currently in an active or worsening state - You have a diagnosed mental disorder Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTEchocardiography

Transthoracic echocardiography at rest: with determination of epicardial fat tissue thickness, epicardial adipose tissue thickness (EAT), E/e', interventricular septum thickness, left ventricular posterior wall thickness, and end-diastolic dimension

DIAGNOSTIC_TESTSpirometry

Spirometry is the most common of the pulmonary function tests, which measures the lung capacity and airway patency (volume and speed of air) during quiet and forced breathing.

DIAGNOSTIC_TESTBody plethysmography

Body plethysmography is a non-invasive lung function test performed in a sealed booth (body box) that measures total lung volume, functional residual capacity, and airway resistance by using Boyle's Law to track pressure and volume changes as a patient breathes, providing crucial data for diagnosing conditions like COPD and asthma, and differentiating them from other lung disorders

DIAGNOSTIC_TEST6-Minute Walk Test (6MWT)

The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity

DIAGNOSTIC_TESTlaboratory biomarker analysis

Routine and special laboratory tests