RecruitingNCT07376616

Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.

Sponsor

Fundacin Biomedica Galicia Sur

Enrollment

242 participants

Start Date

May 19, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Heart rate variability (HRV) provides a non-invasive assessment of autonomic control of the nervous system over the heart. During pregnancy, the cardiovascular system adapts significantly, affecting HRV and hemodynamics. Studying the relationship between HRV and hemodynamic changes is critical to understanding and monitoring cardiovascular health during pregnancy and postpartum, and predicting potential complications.

Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria5

Over 18 years of age
Pregnancy from the third month of gestation
No pre-existing cardiovascular disease
Good cognitive level
Sign informed consent

Exclusion Criteria22

Diabetes mellitus
Hyperthyroidism
Hypothyroidism
Chronic hypertension diagnosed before pregnancy
Heart failure
Ischemic heart disease or malignant ventricular arrhythmias (ventricular fibrillation, ventricular tachycardia, grade 2 or 3 AV block, atrial fibrillation in patients with Wolff-Parkinson- White syndrome, paroxysmal fibrillation or flutter with rapid ventricular response and hemodynamic deterioration, uncontrolled supraventricular tachycardia)
Exercise-induced ischaemia
Unstable angina
Disease not susceptible to revascularization
Associated valvular heart disease
Chronic kidney disease
Degenerative neurological condition
Brain aneurysms
Arteriovenous malformations
History of transient cerebral infarction (ICTUS)
Migraines diagnosed
Epilepsy
Brain or spinal cord injury
Tumors
Diseases of the respiratory tract
Diseases of lung tissue
Diseases of pulmonary circulation