Role of Exercise in PRISm and Subsequent Development of COPD
Role of Exercise in Functional Capacity of Smokers and Subsequent Development of Chronic Obstructive Pulmonary Disease
The University of Hong Kong
90 participants
Jul 14, 2025
INTERVENTIONAL
Conditions
Summary
Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted. While the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.
Eligibility
Inclusion Criteria5
- Age 18 or above
- Smoker/ ex-smoker
- Spirometry shows PRISm, with FEV1/FVC \>= 0.7 and FEV1 \<80% predicted
- Ambulatory to walk
- Able to give informed consent
Exclusion Criteria5
- Age below 18
- Non-smoker
- Spirometry does not show PRISm/ unable to perform spirometry
- Requires assistance for walking
- Unable to give informed consent
Interventions
Participants will attend telehealth physiotherapy class for exercise. Smoking cessation advice will be given.
Participants will exercise with walking. Smoking cessation advice will be given.
No exercise instruction will be given. Participants are encouraged to exercise. Smoking cessation advice will be given.
Locations(1)
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NCT07387432