Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries
A Comparative Study Between Ultrasound Guided Combined Rhomboid Intercostal and Sub- Serratus Plane Blocks and Erector Spinae Plane Block as Perioperative Analgesia in Mastectomy Surgeries in Cancer Breast Patients
National Cancer Institute, Egypt
40 participants
Jan 1, 2026
INTERVENTIONAL
Conditions
Summary
Acute post-mastectomy pain can cause adverse impacts on the patients as delayed discharge from post-operative recovery area, impairs pulmonary and immune functions, increases risk of ileus, thromboembolism, myocardial infarction and may lead to increased length of hospital stay. It is also an important factor leading to the development of chronic post mastectomy pain syndrome (PMPS) in almost half of the patients. Various regional anesthetic techniques have been described for postoperative pain relief after mastectomy, for example, thoracic epidural anesthesia, intercostal nerve block, paravertebral block, serratus anterior plane block, and pectoral nerve I and II blocks. All of them offer satisfactory pain relief after mastectomy. Erector spinae plane block is a novel para-spinal regional anesthesia technique, , promises to provide effective visceral as well as somatic analgesia after carcinoma of the breast surgeries. The ultrasound-guided rhomboid intercostal block sub-serratus plane block (RISS) is a novel analgesic technique The RISS block anesthetizes the lateral cutaneous branches of the thoracic intercostal nerves and can be used in multiple clinical settings for chest wall and upper abdominal analgesia
Eligibility
Inclusion Criteria5
- Breast cancer female patients.
- ASA class II and III.
- Age ≥ 18 and ≤ 60 Years.
- Body mass index (BMI): \> 20 kg/m2 and \< 35 kg/m2.
- Type of surgery; elective breast cancer surgery (either modified radical mastectomy or conservative breast surgery) combined with axillary dissection.
Exclusion Criteria5
- Patient refusal.
- Age \<18 years or \>65 years.
- BMI \<20 kg/m2 and \>35 kg/m2.
- Major medical conditions.
- Pregnancy or lactation.
Interventions
Ultrasound Guided Combined Rhomboid Intercostal Sub-serratus Plane Blocks
Erector Spinae Plane Block
Locations(1)
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NCT07390448