RecruitingNot ApplicableNCT07390448

Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries

A Comparative Study Between Ultrasound Guided Combined Rhomboid Intercostal and Sub- Serratus Plane Blocks and Erector Spinae Plane Block as Perioperative Analgesia in Mastectomy Surgeries in Cancer Breast Patients


Sponsor

National Cancer Institute, Egypt

Enrollment

40 participants

Start Date

Jan 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Acute post-mastectomy pain can cause adverse impacts on the patients as delayed discharge from post-operative recovery area, impairs pulmonary and immune functions, increases risk of ileus, thromboembolism, myocardial infarction and may lead to increased length of hospital stay. It is also an important factor leading to the development of chronic post mastectomy pain syndrome (PMPS) in almost half of the patients. Various regional anesthetic techniques have been described for postoperative pain relief after mastectomy, for example, thoracic epidural anesthesia, intercostal nerve block, paravertebral block, serratus anterior plane block, and pectoral nerve I and II blocks. All of them offer satisfactory pain relief after mastectomy. Erector spinae plane block is a novel para-spinal regional anesthesia technique, , promises to provide effective visceral as well as somatic analgesia after carcinoma of the breast surgeries. The ultrasound-guided rhomboid intercostal block sub-serratus plane block (RISS) is a novel analgesic technique The RISS block anesthetizes the lateral cutaneous branches of the thoracic intercostal nerves and can be used in multiple clinical settings for chest wall and upper abdominal analgesia


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This trial is comparing two types of nerve block techniques used to control pain during and after breast cancer surgery (mastectomy or breast-conserving surgery with lymph node removal). The goal is to find out which approach — the rhomboid intercostal sub-serratus plane block or the erector spinae plane block — provides better pain relief. **You may be eligible if...** - You are a woman aged 18 to 60 years old - You have breast cancer and are scheduled for elective breast surgery combined with axillary (underarm lymph node) dissection - Your BMI is between 20 and 35 - You are classified as ASA physical status II or III (meaning you have mild to moderate health conditions but are otherwise manageable for surgery) **You may NOT be eligible if...** - You are younger than 18 or older than 65 - Your BMI is below 20 or above 35 - You have major medical conditions that make surgery higher risk - You are pregnant or breastfeeding - You refuse participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREUltrasound Guided Combined Rhomboid Intercostal Sub-serratus Plane Blocks

Ultrasound Guided Combined Rhomboid Intercostal Sub-serratus Plane Blocks

PROCEDUREErector Spinae Plane Block

Erector Spinae Plane Block


Locations(1)

National Cancer Institute - Cairo University

Cairo, Egypt

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NCT07390448


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