A Study of SH009 Injection in Patients With Advanced Solid Tumors.

This trial is testing a new experimental drug called SH009 in people with advanced solid tumors (cancer that has spread or cannot be removed surgically) who have already tried at least one standard treatment. This is an early-phase study primarily focused on safety and determining the right dose, but also looking at whether the drug has anti-cancer effects. **You may be eligible if...** - You are 18 or older - You have advanced, recurrent, or metastatic solid tumor cancer (such as colorectal, stomach, liver, head and neck, breast, lung, or esophageal cancer) confirmed by biopsy - You have already tried at least one standard treatment and it stopped working or caused intolerable side effects - You have no other acceptable treatment options - You have at least one measurable tumor on imaging **You may NOT be eligible if...** - You have not tried any prior treatment - You have serious uncontrolled organ problems (heart, liver, kidneys) - You have certain active infections or serious autoimmune conditions - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.