RecruitingNot ApplicableNCT07394959

Hydration Guided by Remote Dielectric Sensing (ReDS) System for Preventing Acute Kidney Injury in Elderly Patients With Renal Insufficiency for Coronary Angiography and Intervention

Clinical Study on Tailored Hydration by Remote Dielectric Sensing System to Prevent Acute Renal Injury in Elderly Patients With Renal Insufficiency After Coronary Angiography


Sponsor

Chinese PLA General Hospital

Enrollment

320 participants

Start Date

Sep 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Explore the effectiveness and safety of tailored hydration guided by lung water index monitor system for prevention of acute kidney injury after percutaneous coronary intervention for elderly patients with renal insufficiency.


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether using a non-invasive device called a ReDS sensor — which measures fluid levels in the lungs — to guide hydration before and after a cardiac catheterization procedure can reduce the risk of kidney damage (contrast-induced acute kidney injury) in elderly patients who already have some kidney impairment. **You may be eligible if...** - You are 60 or older - You have unstable angina and are scheduled for coronary angiography (an X-ray procedure to look at the heart arteries), which may include a stent procedure - You have chronic kidney disease (estimated GFR below 90 ml/min) **You may NOT be eligible if...** - You have acute decompensated heart failure or cardiogenic shock (a heart emergency) - You have severe kidney failure (GFR below 30 ml/min) or malignant tumors - You have respiratory failure - You have received contrast dye within the past week - You are allergic to contrast dye Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURETailored hydration guided by ReDS system

If initial lung water index is ≥35%, the hydration rate is 1ml/kg/h; If the initial lung water index is \<35% but ≥20%, the hydration rate is 2ml/kg/h; If the initial lung water index is \<20%, the hydration rate is designed to 5ml/kg/h. We re-check the lung water index after the contrast procedure. If the lung water index is \>35% or if there is a more than 2-fold increase in the lung water index compared to pre-procedure, adjust the fluid infusion rate to 0.5ml/kg/h. If the lung water index after the contrast procedure is ≥20% but \<35%, adjust the fluid infusion rate to 1ml/kg/h. If the lung water index after the contrast procedure is still \<20%, adjust the fluid infusion rate to 5ml/kg/h.


Locations(1)

Chinese PLA general hospital

Beijing, Beijing Municipality, China

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NCT07394959


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