Hydration Guided by Remote Dielectric Sensing (ReDS) System for Preventing Acute Kidney Injury in Elderly Patients With Renal Insufficiency for Coronary Angiography and Intervention
Clinical Study on Tailored Hydration by Remote Dielectric Sensing System to Prevent Acute Renal Injury in Elderly Patients With Renal Insufficiency After Coronary Angiography
Chinese PLA General Hospital
320 participants
Sep 20, 2024
INTERVENTIONAL
Conditions
Summary
Explore the effectiveness and safety of tailored hydration guided by lung water index monitor system for prevention of acute kidney injury after percutaneous coronary intervention for elderly patients with renal insufficiency.
Eligibility
Inclusion Criteria4
- Age ≥ 60 years;
- Patients with unstable angina pectoris are scheduled for percutaneous coronary intervention；
- Patients with chronic renal disease (estimated glomerular filtration rate \< 90 ml/min);
- Sign the informed consent form.
Exclusion Criteria5
- \. Acute decompensated severe heart failure or cardiogenic shock;
- \. Malignant tumors, severe renal failure (estimated glomerular filtration rate \< 30 ml/min);
- \. Respiratory failure;
- \. Used contrast media within one week;
- \. Have allergic to contrast medium
Interventions
If initial lung water index is ≥35%, the hydration rate is 1ml/kg/h; If the initial lung water index is \<35% but ≥20%, the hydration rate is 2ml/kg/h; If the initial lung water index is \<20%, the hydration rate is designed to 5ml/kg/h. We re-check the lung water index after the contrast procedure. If the lung water index is \>35% or if there is a more than 2-fold increase in the lung water index compared to pre-procedure, adjust the fluid infusion rate to 0.5ml/kg/h. If the lung water index after the contrast procedure is ≥20% but \<35%, adjust the fluid infusion rate to 1ml/kg/h. If the lung water index after the contrast procedure is still \<20%, adjust the fluid infusion rate to 5ml/kg/h.
Locations(1)
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NCT07394959