RecruitingPhase 2NCT07398287

Efficacy of L-menthol on Breathlessness in Interstitial Lung Disease

Effect of L-menthol on Breathlessness and Exercise Capacity in Interstitial Lung Disease: a Randomized Crossover Trial

Sponsor

Region Skane

Enrollment

20 participants

Start Date

Apr 13, 2026

Study Type

INTERVENTIONAL

Conditions

Interstitial Lung Disease (ILD)

Summary

The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Interstitial lung disease (ILD).

Eligibility

Min Age: 18 Years

Inclusion Criteria5

The subject has given written consent to participate in the study
Physician diagnosis of fibrosing ILD according to international guidelines
age 18 years or older
able to cycle
able to understand and talk Swedish to participate in the study procedures, as judged by the Investigators.

Exclusion Criteria6

Resting peripheral oxygen saturation (SpO2) < 92%
hospitalization or clinical instability during the last four weeks
treatment with supplementary oxygen at rest or during exercise
contraindication to exercise testing in accordance with clinical practice guidelines
expected survival shorter than six months as judged by the Investigator
medical conditions including congestive heart failure, acute coronary artery disease, neuromuscular diseases, severe psychiatric illness, and olfaction disorder.