RecruitingPhase 2NCT07403487

Phase II Trial of RC1416 Injection in Asthma

A Randomized, Double-blind, Placebo-controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of RC1416 Injection in Adult Patients With Moderate to Severe Asthma

Sponsor

Nanjing RegeneCore Biotech Co., Ltd.

Enrollment

195 participants

Start Date

Mar 10, 2026

Study Type

INTERVENTIONAL

Conditions

Moderate to Severe Asthma

Summary

This study is a phase II study of RC1416 in subjects with severe uncontrolled asthma. The purpose of the study is to evaluate efficacy and safety of RC1416 in subjects with severe uncontrolled asthma.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called RC1416 and a drug called RC1416 Placebo for people with moderate to severe asthma. The study is currently recruiting participants at 44 locations. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGRC1416

There are two doses in this part. Each subjects will receive the drug by subcutaneous injection.

DRUGRC1416 Placebo

Each subjects will receive the placebo by subcutaneous injection

Locations(44)

Anqiing Municipal Hospital

Anqing, Anhui, China

Wanbei Coal-Electricity Group General Hospital

Suzhou, Anhui, China

China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

The Affiliated Yongchuan Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Gansu Provincial People's Hospital

Lanzhou, Gansu, China

The Third Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

The Affiliated Hospital of North China University of Science and Technology

Tangshan, Hebei, China

Xingtai People's Hospital

Xingtai, Hebei, China

The First Affiliated Hospital of Hebei North University

Zhangjiakou, Hebei, China

Daqing Oilfield General Hospital

Daqing, Heilongjiang, China

The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine

Harbin, Heilongjiang, China

The Third Affiliated Hospital of Qiqihar Medical University

Qiqihar, Heilongjiang, China

Anyang People's Hospital

Anyang, Henan, China

The First Affiliated Hospital of Henan University

Kaifeng, Henan, China

Sanmenxia Central Hospital

Sanmenxia, Henan, China

Xinxiang First People's Hospital

Xinxiang, Henan, China

Yichang Central People's Hospital

Yichang, Hubei, China

Huhhot First Hospital

Hohhot, Inner Mongolia, China

The Affiliated Hospital of Inner Mongolia

Hohhot, Inner Mongolia, China

Nanjing Jiangning Hospital

Nanjing, Jiangsu, China

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, China

Xuzhou Mining Group General Hospital

Xuzhou, Jiangsu, China

Xuzhou Central Hospital

Xuzhou, Jiangsu, China

The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China

The First Hospital of Jilin University

Changchun, Jilin, China

Jilin Central Hospital

Jilin City, Jilin, China

Shengjing Hospital of China Medical University

Shenyang, Liaoning, China

The Fourth Affiliated Hospital of China Medical University

Shenyang, Liaoning, China

Ningxia Hui Autonomous Region People's Hospital

Yinchuan, Ningxia, China

Xi'an International Medical Center Hospital

Xi'an, Shaanxi, China

Heze Municipal Hospital

Heze, Shandong, China

Qilu Second Hospital of Shandong University

Jinan, Shandong, China

The Affiliated Hospital of Jining Medical University

Jining, Shandong, China

Qingdao Municipal Hospital

Qingdao, Shandong, China

Yantai Yuhuangding Hospital

Yantai, Shandong, China

Zibo Central Hospital

Zibo, Shandong, China

Shanghai Pulmonary Hospital (Tongji University Affiliated Shanghai Pulmonary Hospital)

Shanghai, Shanghai Municipality, China

Yuncheng Central Hospital

Yuncheng, Shanxi, China

Chengdu Third People's Hospital

Chengdu, Sichuan, China

Chengdu Fifth People's Hospital

Chengdu, Sichuan, China

Mianyang Central Hospital

Mianyang, Sichuan, China

Affiliated Hangzhou First People's Hospital

Hangzhou, Zhejiang, China

The First Affiliated Hospital of Ningbo University

Ningbo, Zhejiang, China

The Second Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07403487

Related Trials

PULmonary Stimulation for Asthma Relief

NCT07709754

CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma

NCT072411177 locations

A Phase III Study of CM326 in Subjects With Moderate to Severe Asthma

NCT073722871 location

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

NCT0585144383 locations

Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping

NCT063852363 locations