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RecruitingNot ApplicableNCT07403539

Speech Learning and Speech Production in Parkinson's Disease

Relationship Between Speech Perceptual Learning and Speech Production in Parkinson's Disease

Sponsor

State University of New York at Buffalo

Enrollment

50 participants

Start Date

Jan 27, 2026

Study Type

INTERVENTIONAL

Conditions

Parkinson's Disease

Summary

Parkinson's disease, a common movement disorder that results from a breakdown in the brain, often leads to challenges with talking, but less is known about the relationship between difficulties with talking and difficulties with learning to understand speech. By linking these two abilities in individuals with Parkinson's disease using a precision medicine approach, this project seeks to build a basis for new therapies that help people with Parkinson's disease both understand better and speak more clearly.

Eligibility

Min Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how people with Parkinson's disease learn and produce speech, and whether speech therapy approaches can help. Researchers want to understand how the brain controls speech in Parkinson's patients and find better ways to treat speech difficulties. **You may be eligible if...** - You have a diagnosis of Parkinson's disease - You are a native speaker of North American English - You take levodopa (a standard Parkinson's medication) - You live in the United States **You may NOT be eligible if...** - You have any language, hearing, or speech disorder unrelated to Parkinson's disease - You have another major neurological condition such as Alzheimer's disease or have had a stroke - You have significant hearing loss or use a hearing aid or cochlear implant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALIntensity learning

Participants will be asked to pair sentences that vary in their sound intensity to one of three colored squares (red, yellow, or blue)

BEHAVIORALIntensity discrimination

Participants will hear two sentences that are either the same or different in their sound intensity and will be asked to indicate whether the sentences were of the same or different intensities

BEHAVIORALRate learning

Participants will be asked to pair sentences that vary in their spoken rate to one of three colored squares (red, yellow, or blue)

BEHAVIORALRate discrimination

Participants will hear two sentences that are either the same or different in their spoken rate and will be asked to indicate whether the sentences were of the same or different rates

Locations(1)

State University of New York at Buffalo

Buffalo, New York, United States

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NCT07403539

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