RecruitingNot ApplicableNCT07405723

Arm Position and Blood Pressure Measurement Accuracy During Pregnancy

Arm Position and Blood Pressure Measurement Accuracy in Pregnancy: A Randomized Controlled Trial


Sponsor

Sheba Medical Center

Enrollment

300 participants

Start Date

Apr 12, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Accurate blood pressure measurement is essential during pregnancy, as blood pressure readings guide clinical decisions related to the diagnosis and management of hypertensive disorders of pregnancy. Clinical guidelines recommend measuring blood pressure with the arm supported at heart level; however, in routine practice, blood pressure is often measured with the arm in non-standard positions. This study aims to evaluate how different arm positions affect blood pressure measurements in pregnant women. Pregnant women attending a high-risk pregnancy clinic will undergo blood pressure measurements with the arm placed in several commonly used positions, including supported at heart level, supported on the lap, and unsupported at the side. Each participant will have multiple measurements taken during a single clinic visit. The study is designed as a randomized crossover trial with stratification by trimester and chronic hypertension status, allowing each participant to serve as her own control. Participants will be enrolled across all three trimesters of pregnancy, and results will be analyzed separately for each trimester. The primary outcome is the difference in systolic and diastolic blood pressure measurements between arm positions. The findings of this study may help improve the accuracy of blood pressure measurement during pregnancy and inform clinical practice regarding optimal measurement techniques.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 55 Years

Inclusion Criteria5

  • Pregnant women aged 18 to 55 years
  • Singleton or multiple viable intrauterine pregnancy
  • Gestational age corresponding to first, second, or third trimester at the time of enrollment
  • Ability to sit upright comfortably for the duration of blood pressure measurements
  • Ability to understand the study procedures and provide written informed consent

Exclusion Criteria7

  • Preexisting significant cardiac disease (e.g., arrhythmias, congenital heart disease, severe valvular disease)
  • Chronic kidney disease defined as serum creatinine ≥1.5 mg/dL at enrollment
  • Significant upper limb or shoulder conditions that may affect arm positioning or blood pressure measurement (e.g., lymphedema, fractures, prior surgery, arteriovenous fistula)
  • Neurological or musculoskeletal conditions preventing proper positioning
  • Severe preeclampsia, eclampsia, or other acute medical conditions requiring immediate intervention
  • Major fetal anomaly
  • Intrauterine fetal demise

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Interventions

OTHERArm Supported at Heart Level

Blood pressure measurements are obtained with the arm supported at heart level while the participant is seated.

OTHERArm Supported on Lap

Blood pressure measurements are obtained with the arm supported on the participant's lap while seated.

OTHERArm Unsupported at Side

Blood pressure measurements are obtained with the arm unsupported at the participant's side while seated.


Locations(1)

Sheba Medical Center

Ramat Gan, Israel

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NCT07405723


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