RecruitingNot ApplicableNCT07411794

Dexmedetomidine vs Midazolam in Coronary Artery By-pass Surgery

A Comparative Evaluation of Dexmedetomidine and Midazolam ınfusions With Respect to Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting


Sponsor

Cumhuriyet University

Enrollment

60 participants

Start Date

Jan 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The aim is to compare the incidence of postoperative delirium following coronary artery bypass grafting (CABG) between patients receiving dexmedetomidine and those receiving midazolam infusions.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Adult patients scheduled for elective coronary artery bypass graft surgery.

Exclusion Criteria5

  • Patients with renal disorders,
  • Patients with hepatic disorders,
  • Patients with neuropsychiatric disorders,
  • Patients whom informed consent could not be obtained
  • Patients who declined to participate in the study.

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Interventions

DRUGIntravenous Dexmedetomidine infusion + Standard Anesthesia

Following the induction of standard general anaesthesia, dexmedetomidine will be administered as a continuous intravenous infusion at a dose of 0.3-0.7 µg/kg/h.

DRUGintravenous midazolam infusion + Standard anesthesia

Following the induction of standard general anaesthesia, midazolam will be administered as a continuous intravenous infusion at a dose of 0.03-0.06 mg/kg/h.


Locations(1)

Sivas Cumhuriyet University

Sivas, Turkey (Türkiye)

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NCT07411794


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