RecruitingNot ApplicableNCT05036538

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients. A Randomized Controlled Trial on Relaxation Interventions Via Virtual Reality and Binaural Beats.


Sponsor

Heart and Brain Research Group, Germany

Enrollment

125 participants

Start Date

Jul 27, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Patients undergoing cardiac surgery often complain of anxiety before a major operation and the resulting stress. This circumstance is a risk factor for mental problems that may occur after the operation (e.g., delirium or memory deficits). This study aims to prevent these discomforts by a preoperative relaxation intervention.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Elective cardiac surgery (coronary artery bypass surgery, aortic or mitral valve replacement/reconstruction, or combination surgery) with standardized extracorporeal circulation.
  • A sufficiently good knowledge of German is necessary as neuropsychological tests are language-dependent.

Exclusion Criteria8

  • History of acute clinically relevant cognitive impairment of any cause (e.g., dementia, depression, stroke, multiple sclerosis) that may impair neuropsychological evaluation.
  • Contraindications to the presentation of binaural beats or visual stimuli (e.g., epilepsy),
  • Significant hearing loss or astigmatism, which may interfere with optimal perception of auditory and visual stimuli.
  • Taking sedatives on the day of surgery.
  • Unwilling to participate in the relaxation procedure or neuropsychological testing due to deteriorating health, lack of motivation, or other reasons.
  • Participation in interventions that aim to change cognitive or emotional functioning which cannot be systematically controlled by our study team.
  • Participation in an interventional study according to AMG/MPG will also be excluded.
  • Patients with missing informed consent.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEIntervention with natural sounds administered via headphones

The preoperative intervention includes a stress-reducing relaxation phase lasting approximately 30 minutes, during which the patients are presented with nature sounds.

DEVICEIntervention with natural sounds and binaural beats administered via headphones

The preoperative intervention includes a stress-reducing relaxation phase lasting approximately 30 minutes, during which the patients are presented with nature sounds and binaural beats.

DEVICEIntervention with natural sounds and virtual reality administered via headphones and head mounted display

The preoperative intervention includes a stress-reducing relaxation phase lasting approximately 30 minutes, during which the patients are presented with a nature scene in a spherical 360° environment with associated nature sounds.

DEVICEIntervention with natural sounds, binaural beats and virtual reality administered via headphones and head mounted display

The preoperative intervention includes a stress-reducing relaxation phase lasting approximately 30 minutes, during which the patients are presented with a nature scene in a spherical 360° environment with associated nature sounds and binaural beats.


Locations(1)

Kerckhoff Heart Center, Heart and Brain Research Group

Bad Nauheim, Hesse, Germany

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05036538


Related Trials