RecruitingPhase 3NCT07413055

Dexamethasone (4 mg vs. 8 mg) for Pain Control in Dental Implant Surgery

Comparative Efficacy of 4 mg vs. 8 mg Submucosal Dexamethasone in Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial


Sponsor

Oman Ministry of Health

Enrollment

138 participants

Start Date

Feb 5, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site. Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded. Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores. The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.


Eligibility

Min Age: 21 YearsMax Age: 80 Years

Inclusion Criteria5

  • Males \& females
  • Age range (21-80)
  • ASA I \& II according to (American Society of Anesthesiologists) classification
  • Single tooth implant
  • Type 3 \& type 4 implant placement timing (Chen and Buser, 2009)

Exclusion Criteria5

  • Any known allergy to any medications which will be used in the study
  • Smokers/ Alcoholics
  • Pregnant and lactating women
  • Bone augmentation/ sinus lifting required during the surgery
  • The need of antibiotic prophylaxis

Interventions

DRUGDexamethasone 4 Mg/mL Injectable Solution

Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule

DRUGDexamethasone 8Mg Solution for Injection

Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule

DRUGSaline (NaCl 0,9 %) (placebo)

Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule


Locations(1)

Al Nahdha Hospital

Muscat, Oman

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07413055


Related Trials