Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment

Exclusion Criteria14

• Diagnosis of movement disorders such as multiple sclerosis, parkinson's disease
• Diagnosis of Alzheimer's disease,
• Current diagnosis of severe depression, major psychiatric conditions such as bipolar disorder, psychosis, schizophrenia, or alcoholism that could affect the ability to understand and/or cooperate fully with the protocol.
• Significant cerebral vascular disease
• Concomitant medications with significant cholinergic or anticholinergic effects or adverse effects on cognition, including antipsychotics, tricyclic antidepressants, anticonvulsants, sedative/hypnotics, anxiolytics, glucocorticoids (chronic or frequent intermittent),
• Visual/hearing impairment that would significantly impact the ability to participate in psychometric testing.
• Significant medical illness or organ failure, including hepatic or renal failure, unstable cardiac disease,
• Untreated B12 deficiency or hypothyroidism (stable treatment for at least 3 months is allowable).
• Uncontrolled hypertension: over 160 mmHg systolic or 100 mmHg diastolic (stable treatment is allowable).
• Stage 5 renal impairment (GFR less than 15 or dialysis).
• Participation in another clinical trial.
• Prisoners.
• Exercise Contraindications: Any condition that would make moderate-intensity exercise unsafe such as a history of severe aortic stenosis, poorly controlled hypertension, angina, or syncope.
• Lack of Support: No available caregiver or support person for technology assistance