RecruitingPhase 4NCT07418593

Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis


Sponsor

Anna Evans Phillips

Enrollment

80 participants

Start Date

Apr 20, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This project uses the Malabsorption Blood Test (MBT) to identify patients with recurrent acute or chronic pancreatitis who have mild to moderate exocrine pancreatic insufficiency. A subgroup of patients who have response to pancreatic enzyme replacement therapy will enter a randomized, placebo-controlled pilot clinical trial for 8 weeks to identify improvements in quality of life (QOL).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying MBT 2, MBT1, and others for people with chronic pancreatitis, exocrine pancreatic insufficiency, and other related conditions. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGPancreatic Enzyme Replacement Therapy

12 participants who are PERT responders in the MBT will be randomized to receive 8 weeks of PERT (144,000 lipase units daily)

DRUGPlacebo

12 participants who are PERT responders in the MBT will be assigned to receive 8 weeks of placebo therapy

DIAGNOSTIC_TESTMBT1

MBT off PERT

DIAGNOSTIC_TESTMBT 2

MBT on PERT


Locations(2)

Johns Hopkins Medicine

Baltimore, Maryland, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07418593


Related Trials