RecruitingNot ApplicableNCT07422272

Acute Effects of LLLT on Pain Threshold and Pain Tolerance

Examining of the Acute Effects of Low-Level Laser Therapy (LLLT) on Pain Threshold and Tolerance: a Randomized Controlled Trial

Sponsor

European University of Lefke

Enrollment

52 participants

Start Date

Dec 15, 2025

Study Type

INTERVENTIONAL

Conditions

Pain Threshold Acute Pain Low-Level Laser Therapy Pain, Tolerance LLLT vs Sham

Summary

Pain is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Low-Level Laser Therapy (LLLT) has gained attention as a safe, noninvasive intervention with analgesic and anti-inflammatory effects. This study examines whether a single session of LLLT can produce immediate changes in pain threshold and pain tolerance in healthy adults, compared to a sham laser control.

Eligibility

Min Age: 18 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Low-Level Laser Therapy (LLLT) and Sham LLLT for people with acute pain, lllt vs sham, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 35 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELow-Level Laser Therapy (LLLT)

Active LLLT delivered via a 904 nm wavelength Chattanooga model 422 laser at 1000 Hz with a dosage of 0.9 J/cm². The laser is applied for 2 minutes per point over three standardized points near the medial epicondyle (total duration 6 minutes). Standard laser safety eyewear used for both participant and researcher.

OTHERSham LLLT

This is a sham comparator intervention. The procedure replicates the active Low-Level Laser Therapy (LLLT) protocol, including device placement, duration (6 minutes), and use of laser safety eyewear. However, the laser emission is deactivated, and no therapeutic light energy is delivered.