RecruitingPhase 1NCT07422298

A Study to Evaluate the Effect of BMS-986278 on Cardiac Repolarization in Healthy Participants

A Phase 1, Randomized, Double-blind, Positive-controlled, Placebo-controlled, 4-Period Crossover, Thorough QT/QTc Study to Evaluate the Effect of Multiple Doses of BMS-986278 on Cardiac Repolarization in Healthy Participants


Sponsor

Bristol-Myers Squibb

Enrollment

32 participants

Start Date

Feb 19, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the effect of BMS-986278 on the cardiac repolarization in healthy participants.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Inclusion Criteria3

  • Female individuals not of childbearing potential and males.
  • Healthy as determined by medical history, physical examination, vital signs, 12-lead ECG, and clinical laboratory assessments.
  • to 55 years of age, inclusive, at the time of signing the informed consent with a BMI 18.0 to 32.0 kg/m2, inclusive.

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Interventions

DRUGBMS-986278

Specified dose on specified days

DRUGPlacebo

Specified dose on specified days

DRUGMoxifloxacin

Specified dose on specified days


Locations(1)

Worldwide Clinical Trials

San Antonio, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT07422298


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