RecruitingNCT07426211

Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers


Sponsor

Olga Ramich (formerly Pivovarova)

Enrollment

48 participants

Start Date

Jun 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff, comparing employees with night shifts to employees without night shifts.


Eligibility

Min Age: 18 YearsMax Age: 67 Years

Inclusion Criteria10

  • Aged between 18 and 67
  • Male or female
  • Currently employed
  • Body-Mass-Index (BMI) <40 kg/m2
  • Working hours ≥28 hours/week
  • Employees working night shifts (group A): (1) Working night shifts for >1 year, (2) at least two night shifts within the 2-week observation period
  • Employees not working night shifts (group B): No night shifts for >1 year
  • Capable of giving consent
  • Health insurance
  • Good knowledge of German

Exclusion Criteria10

  • Pregnancy and breastfeeding
  • Special diets, e.g. intermittent fasting
  • Severe acute or chronic illnesses, e.g. type 1 diabetes mellitus, liver or kidney disease, heart attack within the last 6 months, stroke or systemic infections, current cancer or cancer within the last 2 years
  • Bariatric surgery
  • Hereditary or acquired blood clotting disorders
  • Severe mental illnesses, e.g. depression, addiction or eating disorders (individual assessment by study staff, if necessary after consultation with a doctor)
  • Holiday in a different time zone (≥ 2 hours time difference) one month before study participation or within the 2-week observation phase
  • Participation in another study that could influence the results of the current study
  • Special drug therapies that could influence the study results (individual assessment by study staff, if necessary after consultation with a physician)
  • Physical or mental difficulties in understanding and following instructions from study staff

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Locations(2)

Charité-Universitaetsmedizin Berlin, Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)

Berlin, Germany

Pflegebereiche CC07 Charité - Universitätsmedizin Berlin Campus Virchow-Klinikum

Berlin, Germany

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NCT07426211


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