RecruitingNot ApplicableNCT07427459

Amygdala Insula Retraining in the Management of Perimenopause Symptoms

Sponsor

Chronic Conditions Research Fund

Enrollment

160 participants

Start Date

Jul 15, 2026

Study Type

INTERVENTIONAL

Conditions

Perimenopause Menopausal Complaints

Summary

The goal of this study is to evaluate a neuroplasticity-based mind-body intervention, Amygdala and Insula Retraining (AIR), compared to a wait-list control in individuals experiencing perimenopausal symptoms. Our research questions include: Does AIR reduce overall perimenopausal symptom burden compared to a wait-list control? Does AIR improve sleep disturbance, vasomotor symptom interference, fatigue, mood, anxiety, and quality of life in perimenopausal individuals? Are symptom changes associated with improvements in autonomic regulation and sleep parameters, as reflected by exploratory wearable measures including heart rate variability?

Eligibility

Sex: FEMALEMin Age: 38 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Amygdala and Insula Retraining (AIR) for people with menopausal complaints and perimenopause. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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