Perimenopause Clinical Trials

17 recruitingLast updated: June 18, 2026

There are 17 actively recruiting perimenopause clinical trials across 8 countries. Studies span Not Applicable, Phase 2. Top locations include Pullman, Washington, United States, Newcastle upon Tyne, United Kingdom, Decorah, Iowa, United States. Updated daily from ClinicalTrials.gov.


Perimenopause Trials at a Glance

17 actively recruiting trials for perimenopause are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 14 trials, with the heaviest enrollment activity in Pullman, Newcastle upon Tyne, and Decorah. Lead sponsors running perimenopause studies include Northumbria University, Washington State University, and Chronic Conditions Research Fund.

Browse perimenopause trials by phase

Treatments under study

About Perimenopause Clinical Trials

Looking for clinical trials for Perimenopause? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Perimenopause trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Perimenopause clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Not Applicable

Amygdala Insula Retraining in the Management of Perimenopause Symptoms

Perimenopause
Chronic Conditions Research Fund160 enrolled1 locationNCT07427459
Recruiting
Not Applicable

12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.

PerimenopausePerimenopausal WomenPerimenopause, Climacteric Syndrome
Northumbria University58 enrolled1 locationNCT07242430
Recruiting
Not Applicable

12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being

PerimenopausePerimenopausal WomenPerimenopause, Climacteric Syndrome
Northumbria University58 enrolled1 locationNCT07235878
Recruiting
Not Applicable

Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being

Quality of LifeSleepGut Microbiota+3 more
King's College London20 enrolled1 locationNCT07599930
Recruiting
Not Applicable

Probiotic Intake and Perimenopausal Psychological Assessments

PerimenopausePerimenopausal WomenPerimenopause-Related Depression+1 more
University of Oxford106 enrolled1 locationNCT07590999
Recruiting
Not Applicable

Exercise in Perimenopause to Improve Cognitive Health

Subjective Cognitive ComplaintsPerimenopause
University of British Columbia50 enrolled1 locationNCT07272174
Recruiting
Not Applicable

The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.

MenopausePerimenopause
Leeds Beckett University72 enrolled1 locationNCT07135232
Recruiting
Not Applicable

Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women

ObesityMenopauseOverweight+1 more
Chang Gung Memorial Hospital40 enrolled1 locationNCT07472881
Recruiting
Not Applicable

Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women

Mental HealthIntermittent FastingPerimenopause
American University of Beirut Medical Center140 enrolled1 locationNCT07481513
Recruiting
Phase 2

Effects of Hemp-Derived Cannabinoids on Menopause Symptoms

MenopausePerimenopause
Washington State University104 enrolled1 locationNCT07393672
Recruiting
Not Applicable

Time-Restricted Eating in Combination With a Low Glycaemic Index Diet on Cognitive Function, Biological Ageing and Metabolic Health in Perimenopause and Menopause.

MenopausePerimenopauseLate-perimenopause
University of Nicosia72 enrolled2 locationsNCT07378787
Recruiting
Not Applicable

Impact of Funcional Exercise and Supplementation in Perimenopausal Women's Health

AgingPerimenopause
University of Valencia90 enrolled1 locationNCT07251296
Recruiting
Not Applicable

Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial

HypertensionPerimenopause
Mayo Clinic70 enrolled1 locationNCT06826755
Recruiting

A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women

PerimenopausePerimenopausal DepressionPerimenopausal Insomnia+5 more
IdentifyHer Limited110 enrolled1 locationNCT07022925
Recruiting
Not Applicable

Hemodynamics After Resistance Training

Perimenopause
University of Michigan50 enrolled1 locationNCT07022340
Recruiting
Phase 2

Impact of Cannabinoids on Menopause Symptoms

MenopausePerimenopause
Washington State University100 enrolled1 locationNCT06831916
Recruiting
Not Applicable

Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety

MenopauseAnxietyPerimenopause+1 more
Dr. Nazanin Alavi25 enrolled2 locationsNCT06865066