RecruitingNot ApplicableNCT07438002

Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment

Effect of Exercise in Patients With Chronic Kidney Disease: TONE Trial


Sponsor

Casa di Cura Dott. Pederzoli

Enrollment

50 participants

Start Date

Sep 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Signature of the informed consent
  • Patients with CKD stage 1 to 5 under conservative treatment
  • Patients undergoing chronic hemodialysis for at least 3 months
  • Age ≥ 18

Exclusion Criteria4

  • Severe cardiovascular disease (NYHA class IV or hypertension class III)
  • TIA or myocardial ischemia within the last three months
  • Anatomical limitations
  • Health conditions detected during the stress test (CPET)

Interventions

OTHERExercise

All participants will be involved in the exercise training three times per week for 24 weeks: endurance exercise training, resistant exercise training

OTHERcontrol

outcome measures


Locations(1)

Ospedale P. Pederzoli Casa di Cura Privata S.p.A.

Peschiera del Garda, Verona, Italy

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NCT07438002


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