Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment

This study is looking at the effects of high-intensity physical exercise on people with chronic kidney disease (CKD) — both those on dialysis and those managing their condition without dialysis. The goal is to understand how exercise impacts kidney disease at different stages. **You may be eligible if...** - You are 18 or older - You have chronic kidney disease (any stage from 1 to 5) managed without dialysis, OR - You have been on hemodialysis for at least 3 months **You may NOT be eligible if...** - You have severe heart failure or very high blood pressure (the most severe categories) - You had a mini-stroke (TIA) or a heart attack within the last 3 months - You have physical limitations that would prevent you from exercising - Your stress test (exercise test) reveals conditions that make exercise unsafe Talk to your doctor to see if this trial is right for you.