RecruitingNCT07439016

LA Function After PFA in Paroxysmal AF

Acute Impairment in Left Atrial and Left Atrial Appendage Function Pre- and Post-Pulse Field Ablation Pulmonary Vein Isolation in Patients With Paroxysmal Atrial Fibrillation: A Prospective Intraprocedural Intracardiac Echocardiography Study


Sponsor

Charles University, Czech Republic

Enrollment

50 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

A prospective study that investigates the changes in LA echocardiographic parameters after PFA for paroxysmal AF.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how a heart procedure called pulsed field ablation (PFA) affects the function of the left atrium (the upper-left chamber of the heart) in people with paroxysmal atrial fibrillation (AF) — a condition where the heart beats irregularly in episodes that come and go on their own. The study uses echocardiography (heart ultrasound) to track changes before and after the procedure. **You may be eligible if...** - You are 18 or older - You have paroxysmal atrial fibrillation (episodes that start and stop on their own) - Your heart is in normal sinus rhythm at the time of the procedure **You may NOT be eligible if...** - You have persistent or long-standing atrial fibrillation (AF that does not stop on its own) - You have previously had a heart ablation procedure - You have significant heart valve disease - You have had your left atrial appendage surgically or procedurally closed Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTLA and LAA function measurements

ICE measurements of the LA and LAA function.


Locations(1)

University Hospital Kralovske Vinohrady

Prague, Czechia

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NCT07439016


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