RecruitingNot ApplicableNCT07439445

Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication

Efficacy and Safety of Simplified Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line Helicobacter Pylori Eradication


Sponsor

Peking University First Hospital

Enrollment

70 participants

Start Date

Apr 25, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

To investigate the efficacy, safety, and compliance of a simplified strategy using vonoprazan plus clarithromycin for first-line treatment in patients with Helicobacter pylori infection, among those infected with strains without clarithromycin resistance gene mutations based on fecal clarithromycin resistance gene detection.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Vonoprazan 20 mg twice daily + clarithromycin 500 mg twice daily for 14 days for people with helicobacter pylori infection. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVonoprazan 20 mg twice daily + clarithromycin 500 mg twice daily for 14 days

Participants receive vonoprazan 20 mg orally twice daily plus clarithromycin 500 mg orally twice daily for 14 consecutive days.


Locations(1)

Peking University First Hospital

Beijing, Beijing Municipality, China

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NCT07439445


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