Helicobacter Pylori Infection Clinical Trials

45 recruitingLast updated: June 18, 2026

There are 45 actively recruiting helicobacter pylori infection clinical trials across 15 countries. Studies span Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1. Top locations include Shanghai, Shanghai Municipality, China, Taipei, Taiwan, Jinan, Shandong, China. Updated daily from ClinicalTrials.gov.


Helicobacter Pylori Infection Trials at a Glance

45 actively recruiting trials for helicobacter pylori infection are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Phase 4 with 15 trials, with the heaviest enrollment activity in Shanghai, Taipei, and Jinan. Lead sponsors running helicobacter pylori infection studies include National Taiwan University Hospital, Shanghai Jiao Tong University School of Medicine, and Tanta University.

Browse helicobacter pylori infection trials by phase

Treatments under study

About Helicobacter Pylori Infection Clinical Trials

Looking for clinical trials for Helicobacter Pylori Infection? There are currently 35 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Helicobacter Pylori Infection trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Helicobacter Pylori Infection clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting

Effect of PPIs on Stool DNA Test for H. Pylori

Helicobacter Pylori Infection
Shanghai Jiao Tong University School of Medicine25 enrolled1 locationNCT07516262
Recruiting
Phase 3

Effect of Bismuth Add-on to Dual Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori Infections
National Taiwan University Hospital990 enrolled1 locationNCT07576959
Recruiting
Not Applicable

Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication

Helicobacter Pylori Infection
Peking University First Hospital70 enrolled1 locationNCT07439445
Recruiting
Not Applicable

Tegoprazan-containing Sequential for H. Pylori

Helicobacter Pylori Infection
Seoul National University Bundang Hospital400 enrolled1 locationNCT06382493
Recruiting
Phase 4

Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication

Peptic ulcer diseaseHelicobacter Pylori InfectionDyspepsia+2 more
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh80 enrolled2 locationsNCT07537634
Recruiting
Not Applicable

Efficacy and Safety of 14-Day Vonoprazan-Based Dual Therapy Versus Quadruple Therapy for Helicobacter Pylori Eradication: A Multicentre, Non-Inferiority Randomized Controlled Trial

Helicobacter Pylori Infections
Yanqing Li372 enrolled2 locationsNCT07179159
Recruiting
Phase 4

Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection

Helicobacter Pylori Infection
National Taiwan University Hospital450 enrolled1 locationNCT05332444
Recruiting
Phase 4

Eradication of Helicobacter Pylori Improves Metabolic Syndrome Through Modulation of Gut Microbiota.

Metabolic SyndromeHelicobacter Pylori Infections
Nanjing First Hospital, Nanjing Medical University120 enrolled1 locationNCT07306988
Recruiting

Registry for the Management of Helicobacter Pylori Infection in Shandong Province

Helicobacter Pylori Infections
Yueyue Li10,000 enrolled2 locationsNCT07335406
Recruiting

Endoscopic Screening of Asymptomatic Patients for Helicobacter Pylori, Intestinal Metaplasia, and Barrett's Mucosa During Screening Colonoscopy

Helicobacter Pylori InfectionsIntestinal MetaplasiaBarett's Esophagus
Sigmund Freud PrivatUniversitat1,000 enrolled1 locationNCT07346521
Recruiting
Not Applicable

H. Pylori Eradication With Argon Plasma During Endoscopy

Helicobacter Pylori InfectionHelicobacter PyloriH.Pylori Infection+2 more
Christopher C. Thompson, MD, MSc20 enrolled1 locationNCT06529159
Recruiting
Phase 2

Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection

Helicobacter Pylori InfectionsHelicobacter InfectionHelicobacter Pylori Gastrointestinal Tract Infection+1 more
Tanta University66 enrolled1 locationNCT07293910
Recruiting
Not Applicable

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy and Bismuth Quadruple Therapy

Helicobacter Pylori Infection
Kaohsiung Medical University552 enrolled1 locationNCT07358130
Recruiting

P-CABs-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori Infection
Yueyue Li1,730 enrolled1 locationNCT07285096
Recruiting
Not Applicable

A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile

Helicobacter Pylori Infection
Miguel O'Ryan Gallardo500 enrolled3 locationsNCT05926804
Recruiting

The GAstric Precancerous Conditions Study

Gastric CancerHelicobacter Pylori InfectionAtrophic Gastritis+1 more
Stanford University600 enrolled1 locationNCT04191551
Recruiting
Phase 4

Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment

Gastric CancerHelicobacter Pylori InfectionGastritis+2 more
Yongquan Shi1,248 enrolled1 locationNCT07139366
Recruiting
Not Applicable

Treatment Efficacy of Regimens With and Without Bismuth in Children With Helicobacter Pylori-Associated Peptic Ulcer Disease

Helicobacter Pylori InfectionPeptic Ulcer
Can Tho University of Medicine and Pharmacy80 enrolled1 locationNCT07260006
Recruiting

Feasibility Study to Diagnose Helicobacter Pylori in the Paediatric Population Using Non-invasive Fecal Analysis

Helicobacter Pylori Infections
Poitiers University Hospital188 enrolled1 locationNCT07083804
Recruiting
Phase 2Phase 3

Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID for H. Pylori Eradication

Helicobacter Pylori Infection
First People's Hospital of Hangzhou240 enrolled1 locationNCT07242456