RecruitingNot ApplicableNCT07440940

Timing of Subcostal TAPB Combined With Rectus Sheath Block for Postoperative Pain After Laparoscopic Cholecystectomy

Effect of Timing of Ultrasound-Guided Subcostal Transversus Abdominis Plane Block Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Trial

Sponsor

Eulji University Hospital

Enrollment

96 participants

Start Date

Feb 23, 2026

Study Type

INTERVENTIONAL

Conditions

Postoperative Pain Laparoscopic Cholecystectomy

Summary

This prospective randomized controlled trial aims to evaluate whether the timing of ultrasound-guided subcostal transversus abdominis plane (TAP) block combined with rectus sheath block (RSB) affects postoperative pain in patients undergoing laparoscopic cholecystectomy. Participants will be randomly assigned to receive the combined regional blocks either before surgical incision or after completion of surgery. The primary outcome is postoperative pain intensity measured using a numerical rating scale. Secondary outcomes include opioid consumption, incidence of postoperative nausea and vomiting, and other recovery parameters. The results of this study may help optimize the timing of abdominal wall blocks to improve postoperative analgesia and recovery following laparoscopic cholecystectomy.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

Elective laparoscopic cholecystectomy
Adults aged 18 to 80 years
Ability to understand the study procedures and provide informed consent
American Society of Anesthesiologists (ASA) physical status I-III

Exclusion Criteria10

Presence of significant pain unrelated to the target disease that may interfere with pain assessment
Known allergy or contraindication to study medications (ropivacaine, acetaminophen, nefopam, or pethidine)
Planned single-port laparoscopic cholecystectomy
American Society of Anesthesiologists (ASA) physical status IV or higher
Infection of the abdominal wall or skin at the injection site, or anatomical abnormalities of the abdominal wall
Major neurological, psychiatric, or systemic diseases that may affect pain perception, treatment response, or study evaluation
Requirement for postoperative mechanical ventilation
Pregnancy or breastfeeding
Considered unsuitable for the study by the investigator
Refusal to participate or inability to provide informed consent

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Interventions

PROCEDUREUltrasound-guided subcostal TAP block combined with rectus sheath block

Ultrasound-guided right subcostal transversus abdominis plane (TAP) block combined with bilateral rectus sheath block (RSB) is performed under sterile conditions using local anesthetic for postoperative analgesia.