RecruitingNot ApplicableNCT07443579

Optimal Mammography View Sequencing in Women With a History of Breast Cancer Undergoing Surveillance Mammography


Sponsor

Royal College of Surgeons, Ireland

Enrollment

400 participants

Start Date

Feb 24, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective, single-centre, parallel-group randomised controlled trial evaluates the optimal sequencing of mammography views in women with a history of breast cancer undergoing surveillance mammography. Women treated with breast-conserving surgery within the previous five years will be randomised 1:1:1:1 to one of four mammography view sequencing groups. The primary objective is to compare patient-reported pain and satisfaction across sequencing groups. Secondary objectives include comparison of image quality (PGMI scoring), compression force, and breast thickness. A total of 400 participants will be enrolled at Beaumont Hospital Breast Care Centre over 2.5 years.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria1

  • Female patients aged 18 years or older History of breast cancer treated with breast-conserving surgery (wide local excision) Undergoing first annual surveillance mammogram following completion of surgery and radiotherapy Within five years of breast cancer treatment May have history of whole-breast or partial-breast radiotherapy May have history of axillary surgery Able and willing to provide informed consent

Exclusion Criteria1

  • Male patients Patients younger than 18 years History of mastectomy History of bilateral wide local excision Lack of capacity to provide informed consent More than five years since completion of breast cancer treatment

Interventions

PROCEDUREMammography View Sequencing

Standard surveillance mammography consisting of MLO and CC views of both treated and untreated breasts. Participants are randomised to one of four predefined sequences determining the order in which views are obtained. No additional imaging beyond standard of care is performed.


Locations(1)

Beaumont RCSI Cancer Centre

Beaumont, Dublin, Ireland

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NCT07443579


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