RecruitingPhase 2NCT07446998

Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss

PLATEAU: Phase 2b Proof-of-Concept Study to Evaluate the Effect on Total Body Weight, Physical Function and Safety of Enobosarm in Patients Treated With Semaglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, for Weight Reduction


Sponsor

Veru Inc.

Enrollment

200 participants

Start Date

Mar 26, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary objective of this study is to assess the effect of enobosarm on total body weight


Eligibility

Min Age: 65 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Enobosarm and a drug called Semaglutide (Wegovy) weekly injection for people with homa-ir, mobility disability, and other related conditions. The study is currently recruiting participants at 10 locations. People eligible for this study include aged 65 Years to 100 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGEnobosarm

Enobosarm is an oral, new chemical entity class, SARM, that has demonstrated tissue-selective, dose-dependent improvement in body composition with increases in muscle mass and reduces fat mass, improves insulin resistance, has no masculinizing effects in women, has neutral prostate effects in men, and no increases in hematocrit. Increases in muscle mass have resulted in improvements in muscle strength and physical function.

DRUGSemaglutide (Wegovy) weekly injection

Semaglutide for Chronic Weight Management


Locations(10)

DM Clinical Research - Phoenix

Phoenix, Arizona, United States

DM Clinical Research - MIA

Doral, Florida, United States

Universal Axon Clinical Research (Rovia - UACR)

Doral, Florida, United States

Paramo Health

Miami, Florida, United States

IMIC Research a Rovia Clinical Research Company

Miami, Florida, United States

Paramo Health

Miami, Florida, United States

UD Research

Atlanta, Georgia, United States

Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States

Centennial Medical Group (CMG)

Columbia, Maryland, United States

SKY Integrative Medical Center

Ridgeland, Mississippi, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07446998


Related Trials