RecruitingNCT07450612
Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection
Sponsor
San Raffaele University
Enrollment
1,200 participants
Start Date
Jan 1, 2024
Study Type
OBSERVATIONAL
Summary
This is an multicenter study that will test the diagnostic accuracy of a blood test (i.e., a liquid biopsy) for the diagnosis of colorectal cancer (CRC), advanced adenomas (AAs), as well as Lynch-syndrome associated cancers. Additionally, a pre-planned analysis will evaluate the use of this liquid biopsy as a tool for molecular residual disease monitoring purposes.
Eligibility
Min Age: 18 Years
Inclusion Criteria3
- All individuals included in the study need to have had a colonoscopy at the time of blood sampling.
- Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
- Received standard pathological and endoscopic diagnosis and assessment for cohort assignment
Exclusion Criteria2
- Lack of informed consent
- Inflammatory bowel disease
Interventions
DIAGNOSTIC_TESTBEACON
A panel of circulating microRNA, whose expression level is tested in cell-free and exosome-derived samples
Locations(4)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07450612