RecruitingNot ApplicableNCT07452562

Hesperidin RCT in MS

A Randomized, Placebo-Controlled Trial of Hesperidin for Fatigue,Mood, and Cognitive Function in Multiple Sclerosis

Sponsor

Swansea University

Enrollment

60 participants

Start Date

Jan 7, 2026

Study Type

INTERVENTIONAL

Conditions

Multiple Sclerosis

Summary

This study is a randomised, double-blind, placebo-controlled trial investigating the effects of Hesperidin supplementation on cognitive function, fatigue, and stress. Participants will be randomly assigned to receive either 500mg of Hesperidin or a matching placebo daily for 12 weeks. The primary outcome is fatigue, with secondary outcomes including cognitive performance and mood. The trial seeks to determine if this dietary intervention offers symptom-alleviating benefits.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether hesperidin—a natural compound found in citrus fruits—can benefit people with multiple sclerosis (MS). Researchers believe it may have anti-inflammatory properties that could help manage MS symptoms or slow progression. **You may be eligible if...** - You have been diagnosed with multiple sclerosis - You are 18 years old or older **You may NOT be eligible if...** - You have known food allergies or intolerances, particularly to citrus - You have significant ongoing digestive or stomach problems - You are under 18 years old Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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