Multidimensional Correlation Analysis of Heart Rate Variability and Weaning Assessment Parameters in Critically Mechanically Ventilated Patients
Fu Jen Catholic University Hospital
100 participants
Dec 9, 2025
OBSERVATIONAL
Conditions
Summary
Background: Conventional weaning assessments are widely used but often affected by factors such as poor patient cooperation, neuromuscular issues, or unstable consciousness, leading to uncertainty in extubation timing. Studies have shown that HRV differs significantly between successful and failed extubation cases. However, most research features small sample sizes, focuses on single HRV indicators, and lacks integration with traditional assessments, limiting HRV's clinical application. Effect: The study aims to develop a predictive model combining HRV and traditional weaning indicators to provide a more objective and sensitive physiological reference for ventilator weaning decisions in critical care settings.
Eligibility
Plain Language Summary
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Interventions
This study will analyze changes in HRV time and frequency domain parameters during SBT, extubation, and post-extubation to evaluate their predictive value for weaning outcomes.
Locations(1)
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NCT07455214