RecruitingNCT07098611

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score (REXs STUDY)


Sponsor

Medipol University

Enrollment

470 participants

Start Date

Jun 15, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Liberation from mechanical ventilation involves three steps: weaning, readiness assessment, and extubation. Readiness is determined using clinical criteria such as improvement of the underlying condition, hemodynamic stability, and adequate respiratory effort. Successful extubation is defined as not requiring invasive support within 48 hours. Due to the complexity of ICU patients, various clinical parameters and multi-component scores have been developed to predict extubation success. This study aims to develop and evaluate a multi-component score, the Readiness for EXtubation score (REXs), to predict extubation readiness in ICU patients under invasive mechanical ventilation.


Eligibility

Min Age: 18 YearsMax Age: 89 Years

Inclusion Criteria1

  • \- Patients who are in the weaning process from mechanical ventilation after being connected to invasive mechanical ventilation in the intensive care unit.

Exclusion Criteria5

  • Patients without legal guardian consent.
  • Tracheostomized patients.
  • Patients enrolled in other studies.
  • Individuals with diaphragmatic pacers.
  • Pregnant patients.

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Locations(7)

University of Magallanes

Punta Arenas, Chile

Cairo University

Cairo, Egypt

Shahid Beheshti University of Medical Sciences

Tehran, Iran

A.O.R.N. "Dei Colli" Monaldi Hospital

Naples, Italy

Monaldi-Cotugno Hospital

Naples, Italy

Hospital General Universitario Morales Meseguer

Murcia, Spain

İstanbul Medipol University

Istanbul, Turkey (Türkiye)

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NCT07098611


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