RecruitingPhase 1Phase 2NCT07457125

The Effect of CB-Exo-A600 in Mild to Moderate Alzheimer's Disease

The Safety and Preliminary Efficacy of Exosomes Derived From Umbilical Cord Mesenchymal Stem Cell (CB-Exo-A600) in Mild to Moderate Alzheimer's Disease


Sponsor

Xuanwu Hospital, Beijing

Enrollment

33 participants

Start Date

May 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study is divided into two phases: a dose-escalation phase and an expansion cohort phase. The dose-escalation phase is a single-center study, while the expansion cohort phase is a multicenter, prospective, randomized, double-blind, placebo-controlled study.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called A placebo of exosomes derived from umbilical cord mesenchymal stem cell for intranasal drop and a drug called Exosomes derived from umbilical cord mesenchymal stem cell for intranasal drop for people with mild to moderate alzheimer's disease. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGExosomes derived from umbilical cord mesenchymal stem cell for intranasal drop

Specification: 2.0 mL/vial. Particle concentration: (Low) 0.75 × 10¹⁰ Particles/mL, (Medium) 1.50 × 10¹⁰ Particles/mL, (High) 3.00 × 10¹⁰ Particles/mL.

DRUGA placebo of exosomes derived from umbilical cord mesenchymal stem cell for intranasal drop

Specification: 2.0 mL/vial.


Locations(1)

Xuanwu Hospital, Capital Medical University

Beijing, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07457125


Related Trials