Group vs Individual MDMA-Assisted Therapy for PTSD After the October 7, 2023 Events

This study is comparing group therapy versus individual therapy, both combined with MDMA (commonly known as ecstasy), for treating PTSD in people affected by the October 7, 2023 attacks in Israel. The goal is to find out whether group or one-on-one sessions work better for trauma recovery. **You may be eligible if...** - You are at least 18 years old - You have a current PTSD diagnosis linked to the October 7, 2023 events or what followed - You have moderate to severe PTSD symptoms (score of 36 or higher on a standard checklist) - You are fluent in Hebrew - You were in some form of psychotherapy before the study - You have a support person (friend or family member) who can be contacted in an emergency - You have a stable address for the next 6 months **You may NOT be eligible if...** - You have a history of schizophrenia, bipolar disorder, or dissociative identity disorder - You currently have serious suicidal thoughts or a recent suicide attempt (within the last 6 months) - You have uncontrolled high blood pressure or a history of heart attack, stroke, or dangerous heart rhythms - You have a severe substance use disorder - You have lost a close person in the past 6 months - You are expected to be on active military duty in the next 12 months - You weigh less than 48 kg Talk to your doctor to see if this trial is right for you.