Skin Conductance for Predicting Spinal Anesthesia-Induced Hypotension in Geriatric Urologic Oncology Patients
Skin Conductance as a Predictor of Spinal Anesthesia-Induced Hypotension in Geriatric Oncology Patients
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
102 participants
Dec 22, 2025
OBSERVATIONAL
Conditions
Summary
Spinal anesthesia-induced hypotension is a common and clinically significant complication in elderly patients undergoing oncologic surgery. Early identification of patients at risk for hemodynamic instability remains a major challenge in perioperative management. Skin conductance reflects sympathetic nervous system activity and may provide a noninvasive indicator of autonomic responses. This prospective observational study aims to evaluate whether skin conductance measurements can predict the development of hypotension following spinal anesthesia in geriatric oncology patients undergoing urologic surgery. The findings may contribute to improved perioperative monitoring and early risk stratification in this vulnerable patient population.
Eligibility
Inclusion Criteria4
- Patients aged 65 years and older
- Patients scheduled for elective urologic oncology surgery under spinal anesthesia
- American Society of Anesthesiologists (ASA) physical status I-III
- Patients who provide written informed consent to participate in the study
Exclusion Criteria7
- Refusal to participate or inability to provide informed consent
- Contraindication to spinal anesthesia (e.g., infection at puncture site, coagulopathy)
- Severe cardiac conduction abnormalities or presence of a cardiac pacemaker
- Severe autonomic dysfunction or known neuropathy affecting autonomic responses
- Use of medications that significantly affect autonomic nervous system activity
- Baseline hypotension or hemodynamic instability before spinal anesthesia
- Inability to obtain reliable skin conductance measurements (e.g., severe skin lesions at electrode placement site)
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Interventions
Skin conductance will be continuously monitored using a noninvasive electrodermal activity monitoring device to assess sympathetic nervous system activity during the perioperative period. Measurements will be recorded before and after spinal anesthesia and evaluated in relation to the development of spinal anesthesia-induced hypotension.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07481851