RecruitingNot ApplicableNCT07488026

Effects of the Stimulation Site of tsMS With TMS on Functional Mobility in Individuals With Parkinson's Disease

Effects of the Stimulation Site of Trans-spinal Magnetic Stimulation Combined With Transcranial Magnetic Stimulation on Functional Mobility in Individuals With Parkinson's Disease

Sponsor

Universidade Federal de Pernambuco

Enrollment

30 participants

Start Date

Jan 5, 2026

Study Type

INTERVENTIONAL

Conditions

Spinal Cord Stimulation Gait Disorders Parkinson's Disease (PD)Transcranial Magnetic Stimulation

Summary

This randomized clinical trial aims to compare the effects of two different trans-spinal magnetic stimulation (tsMS) application sites, cervical versus thoracic, when combined with repetitive transcranial magnetic stimulation (rTMS), on functional mobility in individuals with Parkinson's disease (PD). Participants diagnosed with PD will be randomized into two intervention groups (rTMS + cervical tsMS or rTMS + thoracic tsMS) and will undergo 10 treatment sessions. Outcomes will include functional mobility, gait speed, motor function, freeing of gait, balance, quality of life, global perceived improvement and adverse events. The study is expected to identify the most effective tsMS application site to enhance mobility and motor outcomes in PD, contributing to the optimization and standardization of tsMS protocols as an adjunct therapy.

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Cervical Trans-spinal Magnetic Stimulation, a medical device called Repetitive Transcranial Magnetic Stimulation, and others for people with gait disorders, parkinson's disease (pd), and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 40 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERepetitive Transcranial Magnetic Stimulation

Repetitive transcranial magnetic stimulation applied over the primary motor cortex using standardized stimulation parameters.

DEVICECervical Trans-spinal Magnetic Stimulation

Trans-spinal magnetic stimulation applied at the cervical level using standardized stimulation parameters.

DEVICEThoracic Trans-spinal Magnetic Stimulation

Trans-spinal magnetic stimulation applied at the thoracic level using standardized stimulation parameters.

Locations(1)

Universidade Federal de Pernambuco

Recife, Pernambuco, Brazil

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NCT07488026

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