Parkinson's Disease (PD) Clinical Trials

23 recruiting

Frequently Asked Questions

Common questions about Parkinson's Disease (PD) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled26 locationsNCT07284784
Recruiting
Not Applicable

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

Parkinson's Disease (PD)Essential Tremor
Boston University Charles River Campus80 enrolled2 locationsNCT07455760
Recruiting

Shanghai Clinical Cohort - Parkinson's Disease (Reserve)

Multiple System AtrophyParkinson's Disease (PD)
Ruijin Hospital700 enrolled1 locationNCT07353463
Recruiting
Not Applicable

The Influence of Vibrotactile Stimulation on Self-selected Walking Speed in People With Parkinson's Disease

Parkinson's Disease (PD)
Magnes AG16 enrolled1 locationNCT07308418
Recruiting
Phase 3

Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: a Multi-centre and Multi-modal Approach

Parkinson's Disease (PD)Freezing of GaitFreezing of Gait Symptoms in Parkinson Disease
Radboud University Medical Center60 enrolled1 locationNCT07316296
Recruiting
Phase 2

IMPACT 360 for Parkinson's Disease

Parkinson's Disease (PD)REM Sleep Behavior Disorder
University of British Columbia60 enrolled1 locationNCT07443293
Recruiting
Not Applicable

LIFUS For Neurological Disorders

EpilepsyDystoniaDeep Brain Stimulation+4 more
University Health Network, Toronto50 enrolled1 locationNCT07417280
Recruiting
Not Applicable

Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease

PARKINSON DISEASE (Disorder)Parkinson's Disease (PD)
University of Minnesota75 enrolled1 locationNCT07226284
Recruiting
Not Applicable

Quantification of Hsp90 in the Human Brain

Amyotrophic Lateral Sclerosis(ALS)Alzheimer's Disease(AD)Parkinson's Disease (PD)
Universitaire Ziekenhuizen KU Leuven48 enrolled1 locationNCT07380204
Recruiting

Comprehensive Assessment of Neurodegeneration and Dementia

DementiaMild Cognitive Impairment (MCI)Subjective Cognitive Impairment+7 more
McGill University1,573 enrolled19 locationsNCT03402919
Recruiting
Not Applicable

Electrophysiology-based DBS Programming for PD

Parkinson's Disease (PD)
University of Florida30 enrolled1 locationNCT07348705
Recruiting

Pairing Subjective Patient Rating and DBS Programming

Parkinson's Disease (PD)
Ludwig-Maximilians - University of Munich25 enrolled1 locationNCT07336199
Recruiting
Early Phase 1

Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's Disease

Parkinson's DiseaseParkinson's Disease (PD)Parkinson's Disease (Disorder)
Invicro22 enrolled1 locationNCT07348250
Recruiting
Not Applicable

Empower Your Mind to Embrace Your Life: an Online ACT Intervention for Young-Onset Parkinson's Disease

Parkinson's Disease (PD)
University of Coimbra20 enrolled1 locationNCT07310147
Recruiting

Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease

Parkinson's Disease (PD)
AbbVie450 enrolled68 locationsNCT06107426
Recruiting
Phase 1

Research Into the Safety of a New Agent (VT-5006) in People With and Without Parkinson's Disease

Healthy Volunteers (HV)Parkinson's Disease (PD)
Vertero Therapeutics84 enrolled1 locationNCT07310264
Recruiting
Phase 2

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

Parkinson's Disease (PD)
TrueBinding, Inc.62 enrolled14 locationsNCT06773962
Recruiting
Early Phase 1

[18F]ACI-15916 PET in α-synucleinopathies

Parkinson's Disease (PD)Multiple System Atrophy (MSA)Dementia With Lewy Bodies (DLB)
AC Immune SA46 enrolled1 locationNCT06891703
Recruiting

Non-Invasive Fundus Retinal Detection Technology for Early Diagnosis of Parkinson's Disease

Parkinson's Disease (PD)
Second Affiliated Hospital, School of Medicine, Zhejiang University200 enrolled1 locationNCT07244640
Recruiting
Phase 1

A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease

Parkinson's Disease (PD)
Fujita Health University24 enrolled1 locationNCT07170475