RecruitingNot ApplicableNCT07489742

Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy

Effect of Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy: A Randomized Controlled Trial


Sponsor

Tanta University

Enrollment

210 participants

Start Date

Mar 25, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare the effect of ondansetron lozenge and intravenous for prevention of shivering in tonsillectomy.


Eligibility

Min Age: 4 YearsMax Age: 15 Years

Inclusion Criteria4

  • Age from 4 to 15 years.
  • Both sexes.
  • American Society of Anesthesiology (ASA) physical status I-II.
  • Children undergoing tonsillectomy under general anesthesia.

Exclusion Criteria5

  • Allergy to ondansetron.
  • History of sleep apnea.
  • Cardiac and respiratory diseases.
  • Upper respiratory tract infection.
  • Taking corticosteroids.

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Interventions

DRUGOndansetron lozenge

Patients will receive ondansetron lozenge 4 mg (Ondalenz ©), 2 hours before surgery.

DRUGOndansetron intravenous

Patients will receive 4 mg of ondansetron IV just before the surgery.


Locations(1)

Tanta University

Tanta, El-Gharbia, Egypt

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NCT07489742


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