tonsillectomy Clinical Trials

20 recruitingLast updated: May 13, 2026

There are 20 actively recruiting tonsillectomy clinical trials across 11 countries. Studies span Phase 4, Not Applicable, Phase 2, Phase 3. Top locations include Tanta, El-Gharbia, Egypt, Wuhan, Hubei, China, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


tonsillectomy Trials at a Glance

20 actively recruiting trials for tonsillectomy are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Phase 4 with 7 trials, with the heaviest enrollment activity in Tanta, Wuhan, and Beijing. Lead sponsors running tonsillectomy studies include Perth Children's Hospital, Tanta University, and Children's Healthcare of Atlanta.

Browse tonsillectomy trials by phase

Treatments under study

About tonsillectomy Clinical Trials

Looking for clinical trials for tonsillectomy? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new tonsillectomy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about tonsillectomy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Phase 4

Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients

Postoperative PainEsketamineDexmedetomidine+3 more
Peking University First Hospital160 enrolled1 locationNCT07479602
Recruiting
Not Applicable

Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy

ShiveringtonsillectomyIntravenous+2 more
Tanta University210 enrolled1 locationNCT07489742
Recruiting

Adenoidectomy: Correlation Between Individual Factors, Surgical Technique, and Residual Adenoids

tonsillectomy
Fondazione IRCCS Policlinico San Matteo di Pavia1,200 enrolled1 locationNCT07494370
Recruiting
Not Applicable

Glossopharyngeal and Maxillary Nerve Blocks in Adenotonsillectomy

adenotonsillectomyRegional
Cairo University40 enrolled1 locationNCT07379866
Recruiting
Not Applicable

Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy

Childrenadenotonsillectomyemergence agitation+2 more
Tanta University96 enrolled1 locationNCT07345715
Recruiting

A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea

Neurologic DisorderObstructive Sleep ApneaChild Obesity+4 more
University Hospital, Antwerp200 enrolled2 locationsNCT07305168
Recruiting
Phase 4

Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy

Tonsillectomy with or Without Adenoidectomy
Tongji Hospital114 enrolled1 locationNCT07118579
Recruiting
Not Applicable

Comparison of Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy

adenotonsillectomyPropofolCiprofol
Maternal and Child Health Hospital of Hubei Province236 enrolled1 locationNCT06882980
Recruiting

Effect of Neck Hyperextension on Endotracheal Tube Cuff Pressure in Children

Endotracheal CuffAdenoidectomy SurgeryTonsillectomy with or Without Adenoidectomy+1 more
Ankara Ataturk Sanatorium Training and Research Hospital120 enrolled1 locationNCT06767696
Recruiting
Not Applicable

Effectiveness of a mHealth Application as a Family Supportive Tool in Pediatric Otolaryngology Perioperative Process

tonsillectomy
IRCCS Burlo Garofolo180 enrolled1 locationNCT05460689
Recruiting
Phase 4

Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy

PainBleedingtonsillectomy+1 more
Umeå University100 enrolled1 locationNCT03783182
Recruiting
Phase 4

Does melatonin after tonsillectomy enhance sleep and recovery in children (MATES)?

Pain following tonsillectomy surgery
Perth Children's Hospital240 enrolled1 locationACTRN12624000252516
Recruiting
Phase 4

The effect of clonidine on pain post-tonsillectomy in children

Pain following tonsillectomy surgery
Perth Children's Hospital200 enrolled1 locationACTRN12621001606875
Recruiting
Phase 3

Role of celecoxib in postoperative analgesia in paediatric tonsillectomy: a double-blinded, placebo-controlled randomised controlled trial

Paediatric tonsillectomy
Gosford Hospital140 enrolled2 locationsACTRN12621001390875
Recruiting

The Effect of Coblation vs Bizact Tonsillectomy on Post-Operative Pain: a randomised control trial

tonsillectomy
Professor Simon Carney70 enrolled1 locationACTRN12621000537853
Recruiting
Phase 2

STOP : Study of Tranexamic acid On Post Tonsillectomy haemorrhage

Secondary post tonsillectomy haemorrhage
Perth Children's Hospital70 enrolled1 locationACTRN12621000107820
Recruiting
Phase 4

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

Tonsillitistonsillectomy
Children's Healthcare of Atlanta50 enrolled1 locationNCT03625011
Recruiting

Effect of a short post-operative course of oral prednisone on post-operative morbidity following tonsillectomy in children.

recovery after tonsillectomy in children
Healthcare Otago Charitable trust198 enrolled1 locationACTRN12610001006033
Recruiting
Phase 2

Comparison of peritonsillar infiltration of ketamine and dexamethason for postoperative pain relief in children following adenotonsillectomy

postoperative pain after tonsillectomy
Qazvin University of Medical Science.160 enrolled2 locationsACTRN12610000658011
Recruiting
Phase 4

Randomized control study of post-operative pain in plasmaknife versus monopolar tonsillectomy

Post-operative pain after tonsillectomy.
Mr Neil Vallance, ENT (Ear, Nose & Throat) Surgeon100 enrolled1 locationACTRN12607000200482